Anti-allergy pills also known to be called Antihistamine pills, are the best example of anti-allergy medications that treat a wide range of symptoms. They may help prevent flushing during intake of alcohol. Please always consult your doctor before you mix any medication with alcohol. The older, over-the-counter antihistamines such as Benadryl make people drowsy, but newer antihistamines are very safe and effective and cause little or no drowsiness. Claritin and the prescription medication Allegra, do not cause drowsiness. Zyrtec may make a few individuals sleepy and can be taken at night.